Understanding and Managing Inflammation: The Key to Optimising Muscle Growth and Recovery

The Role of Inflammation in Your Training Journey

Inflammation is an essential part of your body’s response to training stimuli, but like most things, it has its complexities.

When you engage in training, your body naturally creates inflammation. This reaction can be more pronounced when you start a new program, change your rep scheme, revisit an exercise you haven’t done in a while, or return from injury. Here we’ll dive into what this inflammation means for your progress and how nutrition can impact it!

Acute vs. Chronic Inflammation: What You Need to Know

There are two types of inflammation you need to be aware of: acute and chronic.

Acute Inflammation: This type of inflammation is a natural and necessary response to exercise stress, injury, or infection. When you experience acute inflammation, physiological changes occur, including increased blood flow, the accumulation of white blood cells, and the appearance of redness, heat, swelling, and pain at the affected site.

This process is crucial for promoting the generation of new cells, allowing your body to heal, adapt, and grow stronger.

Chronic Inflammation: Unlike acute inflammation, chronic inflammation can be detrimental to your progress. It’s important to manage acute inflammation properly to prevent it from becoming chronic, which can hinder recovery and performance.

The Science Behind Inflammation and Muscle Growth

Inflammation tends to be more pronounced during eccentric contractions, where more muscle damage occurs. This leads to the release of inflammatory compounds such as creatine kinase (CK), interleukin 6 (IL-6), and reactive oxygen species (ROS). While some might see inflammation as something to be suppressed, it’s actually a critical component of muscle repair and growth.

The Dual Role of Interleukin 6 (IL-6) in Muscle Growth

IL-6, a key player in the inflammatory response, has a dual role in muscle growth. Short-term spikes in IL-6 after exercise are beneficial as they activate satellite cells, which are essential for muscle repair. However, prolonged elevations in IL-6 can be detrimental. Research by Mitchell et al. (2013) found that while resting levels of IL-6 negatively correlated with muscle growth, post-exercise elevations were positively correlated with muscle hypertrophy.

Okay, so acute inflammation is good, and chronic is bad right?

Correct!

You do not need to dampen every bit of inflammation immediately, you need to manage it to ensure it doesn't become chronic.

Got it? 

Strategies to Manage Acute Inflammation for Optimal Performance

Given the dual nature of inflammation, the goal is to maintain low resting inflammation levels while allowing for post-exercise spikes that stimulate muscle growth. Here’s how you can manage acute inflammation effectively:

  1. Prioritise Rest and Recovery: If you’re consistently sore, consider adding an extra rest day or spacing out your training sessions. For example, avoid training the same muscle groups on consecutive days, such as front squatting on Monday and squat cleaning on Tuesday.

  2. Optimise Nutrient Timing: Consuming protein around your workouts is essential. Ideally, aim for post-workout protein intake, as it has been shown to help lower the inflammatory response to exercise. If you’re still feeling sore, consider adding carbohydrates to your post-workout meal.

  3. Eat a Balanced Diet: Don’t underestimate the power of a well-balanced diet. Loading up on vegetables can help modulate your immune system and manage inflammation.

  4. Ensure Adequate Caloric Intake: Inflammation can be exacerbated by under-fuelling. Ensure you’re consuming enough calories to support recovery and regeneration.

  5. Maintain a Healthy Body Composition: Reducing body fat can help lower overall inflammation, contributing to better recovery and performance.

What to Avoid: Common Pitfalls in Inflammation Management

  1. Overusing Anti-Inflammatory Medications: Relying on Ibuprofen for every minor ache can impede muscle growth. Reserve it for when it’s absolutely necessary.

  2. Excessive Vitamin C and E: Many multivitamins and pre-workouts contain high doses of vitamins C and E, which can blunt your gains. Avoid supplements with more than 500 mg of vitamin C, especially around your workouts.

  3. Cold Therapy: While ice baths can be useful if you're injured, they’re not always beneficial for recovery. Suppressing inflammation too much can also suppress the repair process.

Embrace Some Level Of Inflammation for Growth

Inflammation is not the enemy; it’s a vital component of your body’s adaptation to training. The key lies in managing it effectively to prevent it from becoming chronic, ensuring you continue to make progress toward your performance goals. By understanding and embracing the role of inflammation, you can optimize your muscle growth and recovery, setting the stage for long-term success.


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I’m a performance nutritionist with years of experience helping athletes optimise their nutrition to improve their recovery. See how I can help you here.

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